Working with MELA Sciences, we designed this medical animation to help doctors and their patients …
THE ROLE OF SEROTONIN IN CARCINOID SYNDROME
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admin
In this video, we will discuss tryptophan metabolism as applied to carcinoid syndrome in patients …
APOPTOSIS AND BCL-2
By
Jordan Maire
ABT-199/GDC-0199 is a small molecule drug in co-development by Abbvie and Genentech for the selective inhibition of BCL-2, a key regulator of cellular apoptosis. BCL-2, part of the larger BCL-2 family, is responsible for the sequestration of pro-apoptotic proteins along the mitochondrial membrane. Displacement of these proteins from BCL-2 in cancerous cells may prime these cells for apoptosis.
GLEEVEC (IMATINIB) MOA
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admin
Kit is a receptor tyrosine kinase that activates of a number of pathways that direct cell proliferation, survival, and apoptosis. Mutations in Kit that result in constitutive oligomerization in the absence of ligand can drive continuous oncogenic signaling.
HULUC 63
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admin
PDL BioPharma asked XVIVO to show how a novel humanized antibody, HuLuc 63, appears to …
TUMOR TREATING FIELDS
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Jordan Maire
XVIVO and Novocure have teamed up to illustrate their breakthrough technology for the non-invasive treatment of solid tumors. Tumor Treating Fields, or TTFields, are alternating electric fields that disrupt and trigger death of cancerous cells.
SMALL MOLECULES FOR CANCER TREATMENT
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admin
Understanding the genetic alterations that underlie cancers may help the development of treatments regardless of …
ORGANOIDS
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admin
Organoids can be made to resemble organs or tissues such as gut, kidney, pancreas, liver, breast, prostate, and even brain tissue, all complete with accurate micro-anatomy. Due to their amazing ability to self-organize into tissue structures, researchers at Weill Cornell Medicine have developed a way to grow organoid structures that mimic actual patients’ tumors, and allow our researchers to study how different cancers develop, change, and might respond to various drug therapies.
XERMELO MOA
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admin
XVIVO partnered with Lexicon Pharmaceuticals to create a series of high end medical animations that provide an overview of carcinoid syndrome diarrhea (CSD). The program illustrates how XERMELO, through the inhibition of TPH, turns down the overproduction of serotonin within neuroendocrine tumor cells, helping patients gain control over carcinoid syndrome.
NANOT BIOANIMATION 2020
By
Jordan Maire
Pulsatile blood flow takes you on a ride as a red blood cell through the circulatory system in the Nanot animation. We begin the animation with the role of natural killer (or NK) cells as a part of the innate immune system that defends against cell malfunction as well as foreign particles (like bacteria or viruses). NK cells have a mechanism to identify and destroy damaged or diseased cells.
Working with MELA Sciences, we designed this medical animation to help doctors and their patients …
