The Vaccine Makers Project (VMP) is the classroom-based program of the Vaccine Education Center at Children’s Hospital of Philadelphia. As partners in this educational initiative, XVIVO has created a series of videos illustrating how the human immune system and vaccines work together to fight diseases.
LISTERINE ANTISEPTIC
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Listerine Antiseptic and its dental health benefits are featured in this animation work for Johnson & Johnson. We begin at an interior view of the mouth, showing brushing and flossing to remove plaque from the surface of the tooth. When Listerine Antiseptic is introduced for rinsing, the viewer is taken on an amusement park splash ride inside the mouth.
LIFE CYCLE OF INFLUENZA A – Narrated by: Forest Whitaker
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This science animation was developed for Zirus, a biopharmaceutical company that was working on the development of a new class of antivirals. This video excerpt, taken from a larger program developed for Zirus, uses the H1N1 influenza-A virus to example the mechanism of action a virus takes to infect a host cell.
Trumenba MOA
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Jordan Maire
In this MOA animation, we worked with Pfizer to share their vaccine development against Serogroup B Meningococcal Disease, or MenB. This lethal disease, caused by bacterial meningitis, primarily affects adolescents and young adults.
USING GENETIC ENGINEERING TO MAKE VACCINES
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In the particular case shown in this animation, the plasmid is making the surface protein from the hepatitis B virus. Scientific detail is retained in the animation through the production of messenger RNA and translation by the ribosome to generate the structure of the hepatitis B surface protein.
HOW DOES HEPATITIS B COMBAT THE IMMUNE SYSTEM?
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Jordan Maire
The 8th animation in a series of 9 on the immune system and vaccines shows a swarm of hepatitis B proteins that vastly outnumber the neutralizing antibodies, and the viral particle making its escape to infect another cell
Attenuation: How Scientists Make Live Vaccines
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Jordan Maire
Taming live viruses to teach the human immune system.
ANTIGENIC DRIFT: HOW THE INFLUENZA VIRUS ADAPTS
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Some viruses have adapted mechanisms to evade the body’s defense mechanisms, namely through mutation. Viruses …
THE ADAPTIVE IMMUNE SYSTEM
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In conjunction with the innate immune system, the adaptive immune system protects our body from infection and damage from foreign bodies (like bacteria and viruses). The adaptive immune system provides our body with a targeted defense by producing antibodies, which are made-to-order proteins against a particular feature of a particular invader.
THE INNATE IMMUNE SYSTEM
By
Jordan Maire
This animation depicts the dance of multiple cell types that comprise our innate immune system to identify and remove foreign particles before they can wreak havoc in our body. A live action basketball analogy in the visuals and voice over make this animation highly relatable, helping viewers understand the scale and function of our surface defense mechanisms against foreign particles (like viruses and bacteria).