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Example Type: Mechanism of Action (MOA) Animation

  • QLS-101 MOA

    May 6, 2021

    By admin

    The animation presents fine visual detail of the eye anatomy, including the sinuous path of the episcleral veins and the cross-sectional view of the retina that so closely resembles human anatomy, you would think you were examining someone’s actual eye. With this dynamic and detailed animation, healthcare providers, consumers, and investors can better understand how eye pressure is regulated and how Qlaris Bio is attempting to innovate in the field and address an unmet need in treating increased pressure inside the eye.
    Read More
  • SONNET PLATFORM MOA

    April 29, 2021

    By Jordan Maire

    Sonnet BioTherapeutics requested an animation to help explain how their Fully Human Albumin Binding (FHAB) platform functions and the potential benefits of the platform over existing anti-tumor therapies. With vivid colors and key lighting details, the FHAB is clearly the star of the show in this animation.
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  • VOXELOTOR AN INVESTIGATIONAL DRUG FOR SICKLE CELL DISEASE

    February 4, 2021

    By admin

    In collaboration with Global Blood Therapeutics, our folks here at XVIVO created this medical animation to illustrate the mechanism of action of a potential drug candidate for the treatment of sickle cell disease (SCD).
    Read More
  • IDIOPATHIC PULMONARY FIBROSIS AND THE EFFECTS OF TREATMENT

    February 4, 2021

    By admin

    The animation, developed in partnership with Wedgewood Communications, shows the mechanism of disease for IPF and the mechanism of action for the recently-approved agent OFEV (nintedanib) from Boehringer Ingelheim.
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  • PALOVAROTENE MOA

    February 4, 2021

    By admin

    Fibrodysplasia ossificans progressiva, or FOP, is an extremely rare and debilitating disorder, in which bone …
    Read More
  • APOPTOSIS AND BCL-2

    February 4, 2021

    By admin

    ABT-199/GDC-0199 is a small molecule drug in co-development by Abbvie and Genentech for the selective inhibition of BCL-2, a key regulator of cellular apoptosis. BCL-2, part of the larger BCL-2 family, is responsible for the sequestration of pro-apoptotic proteins along the mitochondrial membrane. Displacement of these proteins from BCL-2 in cancerous cells may prime these cells for apoptosis.
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  • GLEEVEC (IMATINIB) MOA

    February 4, 2021

    By admin

    Kit is a receptor tyrosine kinase that activates of a number of pathways that direct cell proliferation, survival, and apoptosis. Mutations in Kit that result in constitutive oligomerization in the absence of ligand can drive continuous oncogenic signaling.
    Read More
  • XERMELO MOA

    February 4, 2021

    By admin

    XVIVO partnered with Lexicon Pharmaceuticals to create a series of high end medical animations that provide an overview of carcinoid syndrome diarrhea (CSD). The program illustrates how XERMELO, through the inhibition of TPH, turns down the overproduction of serotonin within neuroendocrine tumor cells, helping patients gain control over carcinoid syndrome.
    Read More
  • NANOT BIOANIMATION 2020

    February 4, 2021

    By Jordan Maire

    Pulsatile blood flow takes you on a ride as a red blood cell through the circulatory system in the Nanot animation. We begin the animation with the role of natural killer (or NK) cells as a part of the innate immune system that defends against cell malfunction as well as foreign particles (like bacteria or viruses). NK cells have a mechanism to identify and destroy damaged or diseased cells.
    Read More
  • COBRA PLATFORM MOA Thumbnail

    COBRA PLATFORM MOA

    February 4, 2021

    By Jordan Maire

    Maverick Therapeutics collaborated with the XVIVO team to create a scientific animation that brought to life the highly complex and novel mechanism of action behind Maverick’s pioneering approach to T cell-engaging immunotherapies. A product of brilliant protein engineering, Maverick’s COBRA™ therapeutic platform generates conditionally active bispecific T cell engagers designed to eliminate solid tumors.
    Read More
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