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  • Illustration of a neural synapse showing two purple neuron endings with multicolored neurotransmitters, highlighting glutamate modulation as they are released and received in the synaptic cleft. The background is softly blurred with a light glow.

    GLUTAMATE MODULATION

    Glutamate is the most abundant excitatory neurotransmitter in the brain. Release of glutamate is essential for normal function of neurons, but the levels of this neurotransmitter must be tightly regulated to avoid toxic effects on neurons. XVIVO partnered with Biohaven to animate the glutamate story. The script details normal glutamate signaling, dysfunctional glutamate signaling and …
  • A detailed 3D illustration of intestinal villi, showing elongated finger-like projections with pink outer layers, green central areas, and textured brown surfaces. This vivid depiction highlights their essential role in nutrient absorption and offers insight into conditions like chronic idiopathic constipation.

    CHRONIC IDIOPATHIC CONSTIPATION

    These clips come from a project we developed that discuss the mechanisms of disease of Chronic Idiopathic Constipation (CIC) and Irritable Bowel Syndrome with Constipation (IBS-C). This medical animation depicts the micro-anatomy of the bowel from the level of bowel surface microvilli, down to the traffic of ions and proteins across specialized tight junctions that …