mRNAs as Medicines Animation

Project Overview

As advancements in mRNA science continue to reshape our understanding, Moderna wanted to create a curriculum to inspire and educate learners about the opportunity mRNA presents as a medicine.

Ionizable Lipids Coat mRNA

The primary objective was to create an engaging, informative online lecture that would serve both internal company training and public education. This project consisted of multiple modules, and, for XVIVO, involved producing over 30 minutes of high-quality 3D animation focusing on mRNA technology, molecular and cellular processes, and therapeutic advancements.

RNA Transcription with RNA Polymerase

Goals and Objectives

The key goals of this project were twofold: to enrich internal learning for Moderna’s team and to provide a compelling educational resource for the general public. Internally, the aim was to elevate the understanding of complex scientific topics among employees, fostering a deeper comprehension of emerging medical innovations and their implications.

mRNA Structure

For the public, the goal was to create a visually stimulating and easily digestible educational tool that could spark interest and increase knowledge about mRNA developments in healthcare.

Lipid Nanoparticle Structure

Approach and Execution

To achieve these objectives, our team collaborated closely with Melissa J. Moore, Moderna’s CSO Emeritus & Dean of Moderna University, and Amy Vanko, Moderna’s Director of Learning and Development, to bring key moments of the lecture to life in 3D. The process began with discussion and brainstorming about visuals that would enhance the narration.

Coronavirus Structure

From there we moved onto research and storyboards, balancing accuracy and drama as we designed scenes with detailed structures and expansive cellular landscapes. With confidence in the storyboards, it was then time to begin modeling and animating. From thousands of ribosomes churning out proteins, to the exploration of harnessing cytotoxic T cells with new therapies, our animations provided a comprehensive and intriguing learning experience.

Many Ribosomes

Results and Impact

Moderna’s VP of Learning, Molly Nagler, said, “Thank you for all the great work you have done on mRNA’s as Medicines. The feedback from Moderna learners is rapturous, and we are seeing just how hungry our employees are for beautiful, accessible learning about mRNA science. Thank you for making this dream a reality!”

Red Blood Cells

Melissa Moore said,
“I had the pleasure of collaborating with the exceptional team at XVIVO for over a year and a half on Moderna’s “mRNA as Medicines” educational program. This ambitious project required the development of over thirty minutes of high-quality 3D animation aimed at educating both Moderna employees and the broader public about the science and future applications of mRNA medicines.

From the outset, XVIVO impressed us with their professionalism, scientific accuracy, and creative talent. They showed attention to detail in each scene, especially when depicting the structure of our lipid nanoparticles. They not only produced visually stunning and accessible content, but their team was also incredibly personable, organized, and responsive throughout the project. Their process made it easy to collaborate to create animations that enhanced the content, and ultimately got us really excited!

XVIVO’s dedication to promoting science literacy and their passion for their craft make them a standout in the field of scientific media development. I have collaborated with many companies over the years, and I can confidently say that XVIVO is among the best. Their expertise and enthusiasm were instrumental to the success of our program.”

Ribosome Translation

As the project turns to the public, we are excited to see the response and hope it contributes to increased awareness and interest in medical science.

The project exemplifies how 3D animation can transform the way we educate and inspire audiences, bridging gaps in understanding and promoting a deeper appreciation for scientific advancements.

TLR Dimer Binds to Viral RNA

If you’re interested in enrolling in Moderna’s mRNAs as Medicines course, register here: https://www.coursera.org/learn/mrnas-as-medicines

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