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Flowchart offering a comparison of ARM MATE therapeutic processes. ARM: 1) Synthetic molecule administered, 2) Antibody complex forms, 3) Targets disease. MATE: 1) Monoclonal antibody given, 2) Antibody conjugate administered, each method with distinct MOA targets the disease effectively.

This illustration was developed to showcase two novel Kleo Pharmaceuticals technologies. Antibody Recruiting Molecules (ARM™s) are bispecific molecules which assist in the recruitment of endogenous antibodies to target diseased cells to initiate immune destruction. Monoclonal Antibody Therapy Enhancers (MATE™s) facilitate the chemical engineering of existing antibodies, which are then administered to clients to enhance the immune’s response to target cells.

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