Organoids can be made to resemble organs or tissues such as gut, kidney, pancreas, liver, breast, prostate, and even brain tissue, all complete with accurate micro-anatomy. Due to their amazing ability to self-organize into tissue structures, researchers at Weill Cornell Medicine have developed a way to grow organoid structures that mimic actual patients’ tumors, and allow our researchers to study how different cancers develop, change, and might respond to various drug therapies.
XERMELO MOA
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admin
XVIVO partnered with Lexicon Pharmaceuticals to create a series of high end medical animations that provide an overview of carcinoid syndrome diarrhea (CSD). The program illustrates how XERMELO, through the inhibition of TPH, turns down the overproduction of serotonin within neuroendocrine tumor cells, helping patients gain control over carcinoid syndrome.
NANOT BIOANIMATION 2020
By
Jordan Maire
Pulsatile blood flow takes you on a ride as a red blood cell through the circulatory system in the Nanot animation. We begin the animation with the role of natural killer (or NK) cells as a part of the innate immune system that defends against cell malfunction as well as foreign particles (like bacteria or viruses). NK cells have a mechanism to identify and destroy damaged or diseased cells.
COBRA PLATFORM MOA
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Jordan Maire
Maverick Therapeutics collaborated with the XVIVO team to create a scientific animation that brought to life the highly complex and novel mechanism of action behind Maverick’s pioneering approach to T cell-engaging immunotherapies. A product of brilliant protein engineering, Maverick’s COBRA™ therapeutic platform generates conditionally active bispecific T cell engagers designed to eliminate solid tumors.
Chromosomal Testing in Chronic Lymphocytic Leukemia
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admin
The volatile and unpredictable nature of subclone emergence makes testing for CLL levels essential. By partnering with XVIVO’s animation team, AbbVie was able to communicate the importance of FISH testing and its influence on CLL diagnosis.