Biorez has pioneered the BioBrace, the first ‘biocomposite’ soft tissue scaffold engineered to both mechanically reinforce tendon and ligament repairs, and enhance healing through its unique material properties and open architecture.
The bone marrow produces blood cells, which are exported to the rest of the body through the vasculature present in the bone marrow.
Anemia often manifests as chronic kidney disease progresses. Roxadustat is a drug engineered to inhibit HIF prolyl-hydroxylase. This allows the HIF complex to form which upregulates certain genes leading to an increased production of hemoglobin and red blood cells. Thus treating CKD related anemia.
In collaboration with Global Blood Therapeutics, our folks here at XVIVO created this medical animation to illustrate the mechanism of action of a potential drug candidate for the treatment of sickle cell disease (SCD).
The animation, developed in partnership with Wedgewood Communications, shows the mechanism of disease for IPF and the mechanism of action for the recently-approved agent OFEV (nintedanib) from Boehringer Ingelheim.
Pulsatile blood flow takes you on a ride as a red blood cell through the circulatory system in the Nanot animation. We begin the animation with the role of natural killer (or NK) cells as a part of the innate immune system that defends against cell malfunction as well as foreign particles (like bacteria or viruses). NK cells have a mechanism to identify and destroy damaged or diseased cells.
The blood-brain barrier (BBB) is a highly selective membrane system that prevents unwanted passage of molecules into the brain extracellular fluid. Consequently, the BBB also significantly hinders the effectiveness of drugs used to treat a number of neurological disorders. Roche has engineered a protein module that can greatly enhance the passage of therapeutic agents across the blood-brain barrier. This 3D medical animation depicts the mechanism by which the “Brain Shuttle” module operates.
By age 50, over half of all males will experience some hair loss caused by Androgenetic Alopecia, also known as male pattern baldness. We teamed up with Johnson & Johnson to develop an educational animation to describe the hair growth process, what goes awry in Androgenetic Alopecia, and how Minoxidil can help reverse its effects. …
The Inner Life of the Cell medical animation was created to help educate college students and, along the way, ended up giving XVIVO an orbital boost. Since its development in 2006, the animation has been used worldwide by educators, scientists, and news outlets to help explain the inner life of a cell and inspired other animators and researchers in their own works.
Biorez has pioneered the BioBrace, the first ‘biocomposite’ soft tissue scaffold engineered to both mechanically reinforce tendon and ligament repairs, and enhance healing through its unique material properties and open architecture.